World Destruction - Futari no Tenshi

In a world ruled by anthropomorphic animals. Humans live as slaves, and a group of terrorists dubbed the "World Destruction Committee" intends to destroy the world in rebellion.

A young man, Kyrie, who possesses the power to destroy the world, though he does not know why. Morte, a young woman with a tragic past and who is leader of a terrorist organization plotting to destroy the world. A demi-human named Naja, Morte's childhood friend Agan, a tough bear named Toppy, and a dragon girl named Lia. These beings will come together and journey to destroy the world!

(Source: Solitary Cross)